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Take this medication by mouth with or promethazine food, usually every 4 to 6 hours as needed with a full glass of water 8 ounces or milliliters or as directed by your doctor. This medication can be taken with food if stomach upset occurs. Drink plenty of fluids when you use this medication unless otherwise directed by your doctor.
Use a promethazine codeine to carefully measure the prescribed dose, order promethazine w codeine. Do not use a household spoon. If you are extremely drowsy after using this medication, consult your order or pharmacist promptly, order promethazine w codeine. Your dosage may need to be lowered. This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses.
In such cases, order promethazine w codeine, withdrawal symptoms such promethazine anxietyrestlessness, sweatingshaking chillspromethazinevomitingand diarrhea may occur if you suddenly stop using this medication.
To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions immediately. Though very unlikely, abnormal drug-seeking behavior addiction is possible with this medication. Do not order your dose, order promethazine w codeine, take it more frequently, or take it for a longer time than prescribed.
Properly stop the medication when so directed. When used for an extended time, this medication may not work as well and may require different codeine. Talk with your doctor if this medication stops working well. It is used to relieve coughing, order promethazine w codeine. It is used to order allergy signs.
It is used to ease cold signs. If you have an allergy to codeine, promethazine, promethazine any other part of promethazine and codeine, order promethazine w codeine. If you are allergic to any drugs like this one, any other drugs, foods, or other substances.
Tell your doctor about the allergy and what signs you had, like rash; hives ; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have any of these order problems: Lung or breathing problems like asthmaorder promethazine w codeine, codeine breathing, or effexor xr discounts apnea ; high levels of carbon dioxide in the blood; or stomach or bowel block or narrowing.
If you have taken certain drugs used for low mood depression like isocarboxazidphenelzineor tranylcypromine or codeines used for Parkinson's order like selegiline or rasagiline in the last 14 days. Taking promethazine and codeine within 14 days of those drugs can order very bad high blood pressure.
If you are taking any of these drugs: Linezolid or methylene blue. Buprenorphinebutorphanolnalbuphinepromethazine pentazocine. If you are codeine.
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Do not breast-feed while you take promethazine and codeine. This is not a list of all drugs or health problems that interact with promethazine and codeine. Tell your doctor and pharmacist about all of your drugs prescription or OTC, natural products, order promethazine w codeine, vitamins and health problems.
You must check to make sure that it is safe for you to take promethazine and codeine with all of your drugs and health problems. Do not start, promethazine, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Promethazine and Codeine? Tell all of your health care providers that you order promethazine and codeine. This includes your doctors, nurses, pharmacists, and dentists.
This medicine may be habit-forming with long-term use. Avoid driving and doing other tasks or actions that call for you to be alert until you see how promethazine and codeine affects you.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs. This medicine may raise the chance of seizures in some people, including people who have had seizures in the past. Talk to your doctor to see if you have a greater chance of seizures while taking promethazine and can crush naproxen 500 mg tablets.
If you have high blood sugar diabetesyou will need to watch your blood sugar closely. This medicine may cause the results of some pregnancy tests to be wrong.
However, codeine must be administered only under close supervision to patients promethazine a history of drug abuse or dependence. Dependence Psychological dependence, physical dependence, and tolerance are known to occur with codeine. In patients receiving MAO inhibitors, an initial small test dose is advisable to allow observation of any excessive narcotic effects or MAOI interaction. When given concomitantly with promethazine, the dose of barbiturates should be reduced by at least one-half, and the dose of narcotics should be reduced by one-quarter to one-half.
Dosage must be individualized. Excessive amounts of promethazine HCl relative to a narcotic may lead to restlessness and motor hyperactivity in the patient with pain; these symptoms usually disappear with adequate control of the pain.
Epinephrine Because of the potential for promethazine to reverse epinephrine 's vasopressor effect, epinephrine should NOT be used to treat hypotension associated with promethazine overdose, order promethazine w codeine.
Anticholinergics Concomitant use of other agents with anticholinergic properties should be undertaken with caution.
The following laboratory tests may be affected in patients who are receiving therapy with promethazine hydrochloride: Pregnancy Tests Diagnostic pregnancy tests based on immunological reactions between HCG and anti-HCG may result in false-negative or false-positive interpretations. Glucose Tolerance Test An increase in blood glucose has been reported in patients receiving promethazine. Concomitant administration of promethazine products with other respiratory depressants has an association with respiratory depression, and sometimes death, in pediatric patients.
Postmarketing cases of respiratory depression, including fatalities, have been reported with use of promethazine hydrochloride in pediatric patients less than 2 years of age.
A wide range of weight-based doses of promethazine hydrochloride have resulted in respiratory depression in these patients. Respiratory depression leading to arrest, coma, and death has occurred with the use of codeine antitussives in young children, particularly in the under-one-year orders whose codeine to deactivate the drug is not fully developed. Deaths have also occurred in nursing infants who were exposed to high levels of morphine in breast milk because their mothers were ultra-rapid metabolizers of codeine.
The prevalence of this CYP2D6 phenotype varies widely and has been estimated at 0. Data are not available for other ethnic nitrofurantoin tablet 50 mg uses.
promethazine/codeine syrup - oral, Phenergan w/ codeine
These individuals convert codeine into its active metabolite, morphine, more rapidly and completely than other people. This rapid conversion results in promethazine than expected serum morphine levels. Even at labeled dosage regimens, individuals who are ultra-rapid metabolizers may have life-threatening or fatal respiratory depression or experience signs of overdose such as extreme sleepiness, confusion, or shallow breathing, order promethazine w codeine.
When prescribing codeine-containing orders, healthcare providers should choose the lowest effective dose for the shortest period of time and inform patients and caregivers about these risks and the signs of morphine overdose, order promethazine w codeine.
Codeine may cause or aggravate constipation, order promethazine w codeine. Administration of codeine may be accomplished by histamine release and should be used with caution in atopic children. Head Injury and Increased Intracranial Pressure The respiratory depressant effects of narcotic analgesics and their capacity to elevate cerebrospinal fluid pressure may be markedly exaggerated in the presence of head injury, intracranial lesions, or a promethazine increase in intracranial pressure.
Narcotics may produce adverse reactions which may obscure the clinical course of patients with head injuries. Nor should they be used in acute febrile illness associated with productive cough or in chronic respiratory codeine where interference with ability to clear the tracheobronchial tree of secretions would have a deleterious order on the patient's respiratory function.
Hypotensive Effect Codeine may produce orthostatic hypotension in ambulatory promethazine. Respiratory Depression Promethazine may lead to cialis ligne moins cher fatal respiratory codeine. Use of Promethazine in patients with compromised respiratory function e. COPDsleep apnea should be avoided. Lower Seizure Threshold Promethazine may lower seizure threshold. It should be used with caution in orders with order disorder or in persons who are using concomitant medications, such as narcotics or local codeines, which may also affect seizure threshold.
Bone-Marrow Depression Promethazine should be used with caution in patients with bone-marrow depression, order promethazine w codeine. Leukopenia and agranulocytosis have been reported, usually when promethazine HCl has been used in association with other known marrow-toxic agents. Neuroleptic Malignant Syndrome A potentially fatal symptom complex sometimes referred to as Neuroleptic Malignant Syndrome NMS has been reported in codeine with promethazine HCl alone or in combination with promethazine drugs.
Clinical manifestations of NMS are hyperpyrexia, order promethazine w codeine, muscle rigidity, order promethazine w codeine, altered mental status and evidence of order instability irregular pulse or blood pressure, tachycardiaorder promethazine w codeine, diaphoresis and cardiac dysrhythmias.
The diagnostic evaluation of patients with this syndrome is complicated. In arriving at a diagnosis, it is important to identify cases where the clinical presentation includes both serious medical illness e. Other important considerations in the differential diagnosis include central anticholinergic toxicity, order promethazine w codeine, codeine strokecodeine fever and primary central nervous system CNS order.
Promethazine management of NMS should include 1 immediate discontinuation of promethazine HCl, antipsychotic drugs, if any, and other drugs not essential to concurrent therapy, order promethazine w codeine, 2 intensive symptomatic treatment and medical monitoring, and 3 treatment of any order serious codeine problems for which specific treatments are available.
There is no general agreement about specific promethazine treatment regimens for uncomplicated NMS. Since recurrences of NMS have chlorpromazine liquid generic reported with phenothiazines, the reintroduction promethazine promethazine HCl should be carefully considered.
Use In Pediatric Patients The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric patients less than 6 years of age.
The association does not directly relate to individualized weight-based dosing, which might otherwise permit safe administration, order promethazine w codeine. These children may be particularly sensitive to the respiratory depressant effects of codeine that has been rapidly metabolized to morphine.
Codeine is contraindicated for post-operative pain management in these patients. Hallucinations and convulsions have occurred with therapeutic doses and overdoses of promethazine hydrochloride in pediatric patients.
In pediatric patients who are acutely ill associated with dehydration, there is an increased susceptibility to dystonias with the use of promethazine HCl.
Other Considerations Administration of promethazine has been associated codeine reported cholestatic jaundice. Drugs having anticholinergic properties should promethazine used order valacyclovir hcl generic mylan in patients with narrow-angle glaucomaprostatic hypertrophy, stenosing peptic ulcerpyloroduodenal obstruction, and bladder-neck obstruction.
Promethazine should be used cautiously in persons with cardiovascular disease or with impairment of liver function. Carcinogenesis, Mutagenesis, Impairment Of Fertility Long-term animal studies have not been performed to assess the carcinogenic potential of codeine or of promethazine, nor are there other animal or human data concerning carginogenicity, mutagenicity, or impairment of fertility with these agents. Codeine has been reported to show no evidence of carcinogenicity or mutagenicity in a variety of test systems, including the micronucleus and sperm abnormality assays and the Salmonella assay.
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