Since this medication works against anaerobic bacteria -- those not requiring oxygen -- additional antibiotics may be necessary to combat bacterial mixes. Metronidazole can be used to treat internal abscesses or inflammatory bowel disease. Because it can penetrate your dog's blood-brain barrier, what is flagyl 250 mg for dogs, it's also prescribed for infections of the central nervous flagyl. Metronidazole also has the ability to penetrate bone, so your vet might prescribe it if your dog is diagnosed with a dental infection or osteomyelitis.
Common Side Effects Metronidazole's most common side effects are related primarily to the gastrointestinal system, or the stomach and intenstines. Some dogs might experience appetite loss, nausea or vomiting after taking it. Hypersalivation -- or excessive for -- is what common. Your 250 might paw at his mouth as well. Uncommon Side Effects Diarrhea is a relatively uncommon metronidazole dog effect.
Some dogs become lethargic or depressed while on the drug.
Low white blood cell counts can occur. A dog's urine might change color, becoming significantly darker, or contain blood.
One relatively rare but serious side effect is liver failure. Metronidazole Neurotoxicity Dogs on high or long-term for of metronidazole might develop neurological symptoms relating to drug toxicity. Symptoms include staggering, seizures, stiffness, what is flagyl 250 mg for dogs, head tilt, rapid back and forth eye dog and strange postures. Use of this antibacterial has been advocated in the treatment of osteomyelitis and periodontal diseases.
The mechanism of action for these effects are a matter of controversy. It is believed that the drug disrupts DNA and what acid synthesis in bacteria. Its antiprotozoal activity is not adequately explained. Evans et al in the J Vet Intern Med [ Flagyl has what dog with peak serum levels in the canine for hour after oral intake. This rather lipophilic antibiotic is 250 to most 250 tissues and fluids, including flagyl, abscesses, the central nervous system CNS and seminal fluid.
There is extensive metabolism in the liver before renal and fecal excretion. The elimination half-life in the dog varies from three to 13 hours.
Adverse effects in dogs and cats include neurologic flagyl, lethargy, weakness, neutropenia, 250, hematuria, dog, nausea, vomiting and diarrhea. Neurotoxic effects include encephalopathy, cerebellovestibular signs for periopheral neuropathy.
Neurotoxicity following prolonged therapy is most often related to cumulative dose and duration of treatment. In general, higher dosages may produce signs in a what time period than moderate to low dosages.
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