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This medicine has an opioid drug in it. Opioid drugs can put you at risk for addiction, abuse, and misuse. Misuse or abuse of promethazine and codeine can lead to overdose and death. If you have questions, talk with your doctor. The use of opioid drugs along with a benzodiazepine drug or other drugs that may make you drowsy or slow your actions has led to very bad side effects.

Side effects that have happened include slowed or trouble breathing and deaths. Benzodiazepine drugs include drugs like alprazolam , diazepam , and lorazepam. Benzodiazepine drugs are used to treat many health problems like anxiety , trouble sleeping, or seizures.

Talk with the doctor. Many drugs interact with promethazine and codeine and can raise the chance of side effects like deadly breathing problems. Talk with your doctor and pharmacist to make sure it is safe to use promethazine and codeine with all of your drugs. Avoid alcohol or other drugs and natural products that slow your actions. Get medical help right away if you feel very sleepy, very dizzy, or if you pass out. Caregivers or others need to get medical help right away if the patient does not respond, does not answer or react like normal, or will not wake up.

Very bad and sometimes deadly breathing problems have happened with promethazine and codeine. Get medical help right away if you have slow breathing, shallow breathing, or trouble breathing. Even one dose of promethazine and codeine may be deadly if it is taken by someone else or by accident, especially in children. If promethazine and codeine is taken by someone else or by accident, get medical help right away. Keep all drugs in a safe place.

Keep all drugs out of the reach of children and pets. This medicine is not for use in children younger than 18 years of age. The benefits of taking promethazine and codeine for a cough due to allergies , a cold, or other infection do not outweigh the risks in children. If your child has been given promethazine and codeine or if you have any questions, talk with your child's doctor. Uses of Promethazine and Codeine: It is used to relieve coughing.

It is used to ease allergy signs. It is used to ease cold signs. If you have an allergy to codeine, promethazine, or any other part of promethazine and codeine. If you are allergic to any drugs like this one, any other drugs, foods, or other substances.

Tell your doctor about the allergy and what signs you had, like rash; hives ; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have any of these health problems: Lung or breathing problems like asthma , trouble breathing, or sleep apnea ; high levels of carbon dioxide in the blood; or stomach or bowel block or narrowing. If you have taken certain drugs used for low mood depression like isocarboxazid , phenelzine , or tranylcypromine or drugs used for Parkinson's disease like selegiline or rasagiline in the last 14 days.

Taking promethazine and codeine within 14 days of those drugs can cause very bad high blood pressure. If you are taking any of these drugs: Linezolid or methylene blue. Buprenorphine , butorphanol , nalbuphine , or pentazocine. If you are breast-feeding.

Do not breast-feed while you take promethazine and codeine. This is not a list of all drugs or health problems that interact with promethazine and codeine. Tell your doctor and pharmacist about all of your drugs prescription or OTC, natural products, vitamins and health problems.

You must check to make sure that it is safe for you to take promethazine and codeine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Promethazine and Codeine? Tell all of your health care providers that you take promethazine and codeine. Take this medication by mouth with or without food with a full glass of water 8 ounces or milliliters or as directed by your doctor.

This medication may be taken with food or milk if stomach upset occurs. The dosage is based on your medical condition and response to treatment. If you are using a liquid form, use a medication-measuring device or spoon to carefully measure the prescribed dose.

Do not use a household spoon because you may not get the correct dose. If your liquid form is a suspension, shake the bottle well before each dose. If you are using sustained-release tablets or capsules, swallow the medication whole. Do not crush, chew, or break the tablets or capsules. Doing so can destroy the long action of the drug and may increase side effects. Do not increase your dose or use this product more often or for longer than directed. Your condition will not improve any faster, and your risk of side effects will increase.

This medication may cause withdrawal reactions, especially if it has been used regularly for a long time more than a few weeks or in high doses.

In such cases, withdrawal symptoms such as anxiety , restlessness, sweating , shaking chills, nausea , vomiting , and diarrhea may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions right away. Though it helps many people, this medication has a risk for abuse and may sometimes cause addiction.

Take this medication exactly as directed to lower the risk of addiction.

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